KAFFI -S by Chemisis Pharmaceuticals is a combination antibiotic injection containing Ceftriaxone and Sulbactam. This combination is used to treat a variety of severe bacterial infections, including those of the respiratory tract, urinary tract, skin and soft tissues, and intra-abdominal infections.

• Ceftriaxone: A third-generation cephalosporin antibiotic that works by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. It is effective against a wide range of gram-positive and gram-negative bacteria.
• Sulbactam: A beta-lactamase inhibitor that protects Ceftriaxone from degradation by beta-lactamase enzymes produced by certain bacteria. This enhances the effectiveness of Ceftriaxone against resistant bacterial strains.

The typical dosage and administration of KAFFI -S depend on the type and severity of the infection, as well as the patient’s age and kidney function. It is administered via intramuscular or intravenous injection, usually in a clinical or hospital setting under the supervision of a healthcare professional. Common side effects may include pain or swelling at the injection site, rash, diarrhea, nausea, and headache. Serious side effects are rare but can include severe allergic reactions, Clostridium difficile-associated diarrhea, and changes in blood cell counts. Patients should inform their healthcare provider of any allergies or pre-existing conditions before starting treatment.